Skip to main content


Page 2 of 3

  1. The role of EGCG, a major green tea catechin in breast cancer therapy is poorly understood. The present study tests the hypothesis that EGCG can inhibit the activation of HIF-1α and NFκB, and VEGF expression, ...

    Authors: Jian-Wei Gu, Kristina L Makey, Kevan B Tucker, Edmund Chinchar, Xiaowen Mao, Ivy Pei, Emily Y Thomas and Lucio Miele
    Citation: Vascular Cell 2013 5:9
  2. Notch4 is a member of the Notch family of receptors that is primarily expressed in the vascular endothelial cells. Genetic deletion of Notch4 does not result in an overt phenotype in mice, thus the function of No...

    Authors: Maria José Costa, Xiaoqing Wu, Henar Cuervo, Ruchika Srinivasan, Seth K Bechis, Ellen Cheang, Olivera Marjanovic, Thomas Gridley, Christin A Cvetic and Rong A Wang
    Citation: Vascular Cell 2013 5:7
  3. Infantile hemangiomas are benign vascular tumors primarily found on the skin in 10% of the pediatric population. The etiology of this disease is largely unknown and while large scale genomic studies have exami...

    Authors: Jessica M Stiles, Rebecca K Rowntree, Clarissa Amaya, Dolores Diaz, Victor Kokta, Dianne C Mitchell and Brad A Bryan
    Citation: Vascular Cell 2013 5:6
  4. The body’s vascular system is thought to have developed in order to supply oxygen and nutrients to cells beyond the reach of simple diffusion. Hence, relative hypoxia in the growing central nervous system (CNS...

    Authors: Tom Arnold and Christer Betsholtz
    Citation: Vascular Cell 2013 5:4

    The Erratum to this article has been published in Vascular Cell 2013 5:12

  5. The identification of circulating endothelial progenitor cells (EPCs) has introduced new possibilities for cell-based treatments for stroke. We tested the angiogenic gene expression of outgrowth endothelial ce...

    Authors: Míriam Navarro-Sobrino, Mar Hernández-Guillamon, Israel Fernandez-Cadenas, Marc Ribó, Ignacio A Romero, Pierre-Olivier Couraud, Babette Barbash Weksler, Joan Montaner and Anna Rosell
    Citation: Vascular Cell 2013 5:3
  6. Recently, bisphosphonates (BPs) have been widely used in medical practice as anti-resorptive agents owing to their anti-osteoclatic action. In addition, these compounds are also used for their analgesic action...

    Authors: Dileep Sharma, Saso Ivanovski, Mark Slevin, Stephen Hamlet, Tudor S Pop, Klara Brinzaniuc, Eugen B Petcu and Rodica I Miroiu
    Citation: Vascular Cell 2013 5:1
  7. Citicoline is one of the neuroprotective agents that have been used as a therapy in stroke patients. There is limited published data describing the mechanisms through which it acts.

    Authors: Jerzy Krupinski, Manal Abudawood, Sabine Matou-Nasri, Raid Al-Baradie, Eugen Bogdan Petcu, Carlos Justicia, Anna Planas, Donghui Liu, Norma Rovira, Marta Grau-Slevin, Julio Secades and Mark Slevin
    Citation: Vascular Cell 2012 4:20
  8. Mutations in the RASA-1 gene underlie several related disorders of vasculogenesis. Capillary malformation-arteriovenous malformation (CM-AVM) is one such entity and was recently encountered in a neonate who de...

    Authors: Gerald G Behr, Leonardo Liberman, Jocelyn Compton, Maria C Garzon, Kimberly D Morel, Christine T Lauren, Thomas J Starc, Stephen J Kovacs, Vincent Beltroni, Rachel Landres, Kwame Anyane-Yeboa, Philip M Meyers, Emile Bacha and Jessica J Kandel
    Citation: Vascular Cell 2012 4:19
  9. Loss of endothelial cell integrity and selective permeability barrier is an early event in the sequence of oxidant-mediated injury and may result in atherosclerosis, hypertension and facilitation of transendot...

    Authors: Bryan Simoneau, François Houle and Jacques Huot
    Citation: Vascular Cell 2012 4:18
  10. The current knowledge on molecular pathogenesis of cerebral vascular malformations (CVM), which are believed to arise during development, is very limited. To unravel the molecular mechanisms involved in CVMs, ...

    Authors: Abdulkadir Özkan, Atilla Biçer, Timuçin Avşar, Aşkın Şeker, Zafer Orkun Toktaş, Süheyla Uyar Bozkurt, Ayşe Nazlı Başak and Türker Kılıç
    Citation: Vascular Cell 2012 4:16
  11. Bone marrow derived myeloid cells progressively accumulate in tumors, where they establish an inflammatory microenvironment that is favorable for tumor growth and spread. These cells are comprised primarily of...

    Authors: Michael C Schmid and Judith A Varner
    Citation: Vascular Cell 2012 4:14
  12. Macrophages regulate many developmental and pathological processes in both embryonic and adult tissues, and recent studies have shown a significant role in angiogenesis. Similarly, Wnt signaling is fundamental...

    Authors: Andrew C Newman and Christopher C W Hughes
    Citation: Vascular Cell 2012 4:13
  13. Cellular senescence is associated with cellular dysfunction and has been shown to occur in vivo in age-related cardiovascular diseases such as atherosclerosis. Atherogenesis is accompanied by intimal accumulation...

    Authors: Vincent J D Krouwer, Liesbeth H P Hekking, Miriam Langelaar-Makkinje, Elsa Regan-Klapisz and Jan Andries Post
    Citation: Vascular Cell 2012 4:12
  14. Tuberous sclerosis (TS) is a common autosomal-dominant disorder characterized by tumors of the skin, lung, brain, and kidneys. Monotherapy with rapamycin however resulted in partial regression of tumors, imply...

    Authors: Baskaran Govindarajan, Laura Willoughby, Hamid Band, Adam S Curatolo, Emir Veledar, Suephy Chen, Michael Y Bonner, Martin-Garrido Abel, Marsha A Moses and Jack L Arbiser
    Citation: Vascular Cell 2012 4:11
  15. Natural health products (NHP) which include minerals, vitamins and herbal remedies are not generally considered by medical practitioners as conventional medicines and as such are not frequently prescribed by h...

    Authors: Mark Slevin, Nessar Ahmed, Qiuyu Wang, Garry McDowell and Lina Badimon
    Citation: Vascular Cell 2012 4:9
  16. Heparin is an anticoagulant agent known to have diverse effects on angiogenesis with some reports suggesting that it can induce angiogenesis while a few have indicated of its inhibitory property. Cancer patien...

    Authors: Reji Bhuvanendran Rema, Karthick Rajendran and Malathi Ragunathan
    Citation: Vascular Cell 2012 4:8
  17. Anti-angiogenesis agents and the identification of cancer stem-like cells (CSC) are opening new avenues for targeted cancer therapy. Recent evidence indicates that angiogenesis regulatory pathways and developm...

    Authors: Jian-Wei Gu, Paola Rizzo, Antonio Pannuti, Todd Golde, Barbara Osborne and Lucio Miele
    Citation: Vascular Cell 2012 4:7
  18. The non-destructive assessment and characterization of tridimensional (3D) cell and tissue constructs in bioreactors represents a challenge in tissue engineering. Medical imaging modalities, which can provide ...

    Authors: Julie A Chouinard, Jacques A Rousseau, Jean-François Beaudoin, Patrick Vermette and Roger Lecomte
    Citation: Vascular Cell 2012 4:5
  19. Pleiotrophin (PTN) is a heparin-binding growth factor with significant role(s) in tumour growth and angiogenesis. Although implication of endogenous PTN has been studied in several in vivo models of tumour angiog...

    Authors: Marina Koutsioumpa, Georgia Drosou, Constantinos Mikelis, Katerina Theochari, Dionussios Vourtsis, Panagiotis Katsoris, Efstathia Giannopoulou, Jose Courty, Christos Petrou, Vassiliki Magafa, Paul Cordopatis and Evangelia Papadimitriou
    Citation: Vascular Cell 2012 4:4
  20. Burkitt's lymphoma (BL) is an aggressive Non-Hodgkin lymphoma. Epstein-Barr Virus (EBV) is able to transform B cells and is a causative infectious agent in BL. The precise role of EBV in lymphoma progression i...

    Authors: Jürgen Becker, Ana Covelo-Fernandez, Frederike von Bonin, Dieter Kube and Jörg Wilting
    Citation: Vascular Cell 2012 4:3
  21. Astragali Radix has been used widely for the treatment of cardiovascular and cerebrovascular diseases, and to enhance endurance and stamina in traditional Chinese medicine (TCM) for over 2000 years. The polysa...

    Authors: Guang Hu, Gail B Mahady, Shang Li, Maggie Pui Man Hoi, You-Hua Wang and Simon Ming Yuen Lee
    Citation: Vascular Cell 2012 4:2
  22. Wnt signaling is activated in many types of cancer and normal physiological processes. Various Wnt-related secreted factors may influence angiogenesis both in the tumor microenvironment and in normal tissues b...

    Authors: Marina Planutiene, Kestutis Planutis and Randall F Holcombe
    Citation: Vascular Cell 2011 3:28
  23. Neovascularization (angiogenesis) is a multistep process, controlled by opposing regulatory factors, which plays a crucial role in several ocular diseases. It often results in vitreous hemorrhage, retinal deta...

    Authors: Ravindra Kumar, Sandra Harris-Hooker, Ritesh Kumar and Gary Sanford
    Citation: Vascular Cell 2011 3:27

    The Erratum to this article has been published in Vascular Cell 2012 4:6

  24. Vascular endothelial growth factor (VEGF) blockade is an effective therapy for human cancer, yet virtually all neoplasms resume primary tumor growth or metastasize during therapy. Mechanisms of progression hav...

    Authors: Jason C Fisher, Jeffrey W Gander, Mary Jo Haley, Sonia L Hernandez, Jianzhong Huang, Yan-Jung Chang, Tessa B Johung, Paolo Guarnieri, Kathleen O'Toole, Darrell J Yamashiro and Jessica J Kandel
    Citation: Vascular Cell 2011 3:22
  25. Vascular smooth muscle cell (VSMC) hypertrophy and proliferation occur in response to strain-induced local and systemic inflammatory cytokines and growth factors which may contribute to hypertension, atheroscl...

    Authors: Joseph F Schad, Kate R Meltzer, Michael R Hicks, David S Beutler, Thanh V Cao and Paul R Standley
    Citation: Vascular Cell 2011 3:21
  26. Infantile hemangiomas (IHs) are the most common benign tumor of infancy, yet their pathogenesis is poorly understood. IHs are believed to originate from a progenitor cell, the hemangioma stem cell (HemSC). Rec...

    Authors: Omotinuwe Adepoju, Alvin Wong, Alex Kitajewski, Karen Tong, Elisa Boscolo, Joyce Bischoff, Jan Kitajewski and June K Wu
    Citation: Vascular Cell 2011 3:19
  27. Telatinib (BAY 57-9352) is an orally available, small-molecule inhibitor of vascular endothelial growth factor receptors 2 and 3 (VEGFR-2/-3) and platelet-derived growth factor receptor β tyrosine kinases.

    Authors: Klaus Mross, Annette Frost, Max E Scheulen, Jürgen Krauss, Dirk Strumberg, Beate Schultheiss, Ulrike Fasol, Martin Büchert, Jörn Krätzschmer, Heinz Delesen, Prabhu Rajagopalan and Olaf Christensen
    Citation: Vascular Cell 2011 3:16
  28. The negative feedback system is an important physiological regulatory mechanism controlling angiogenesis. Soluble vascular endothelial growth factor (VEGF) receptor-1 (sFlt-1), acts as a potent endogenous solu...

    Authors: Shakil Ahmad, Peter W Hewett, Bahjat Al-Ani, Samir Sissaoui, Takeshi Fujisawa, Melissa J Cudmore and Asif Ahmed
    Citation: Vascular Cell 2011 3:15
  29. Current limitations to the experimentation on patients with peripheral arterial disease push the development of different preclinical strategies. We investigated both duration of ischemia and blood flow recove...

    Authors: Husain A Al-Mubarak, Talal M Alamri, Saif A Aljabab, Mohammad Atteya, Adrian Quan, Hwee Teoh, Praphulla C Shukla, Subodh Verma, Abdullah Aldahmash, Badr Aljabri, Claudio Napoli and Mohammed Al-Omran
    Citation: Vascular Cell 2011 3:14
  30. Coronary artery disease is a global health concern in the present day with limited therapies. Extensive efforts have been devoted to find molecular therapies to enhance perfusion and function of the ischemic m...

    Authors: Mathews Lisa, Nagaraja Haleagrahara and Srikumar Chakravarthi
    Citation: Vascular Cell 2011 3:13
  31. Poly(ADP-Ribose) polymerase (PARP) activity has been demonstrated fundamental in many cellular processes, including DNA repair, cell proliferation and differentiation. In particular, PARP activity has been rec...

    Authors: Riccardo Caldini, Elena Fanti, Lucia Magnelli, Emanuela Barletta, Elisabetta Tanganelli, Michele Zampieri and Marta Chevanne
    Citation: Vascular Cell 2011 3:12
  32. The angiogenic potential of a cell requires dynamic reorganization of the cytoskeletal architecture that involves the interaction of urokinase-type plasminogen activator receptor (uPAR) with the extracellular ...

    Authors: Rashna D Balsara, Reid Merryman, Farhaad Virjee, Claire Northway, Francis J Castellino and Victoria A Ploplis
    Citation: Vascular Cell 2011 3:10
  33. Vascular endothelial growth factors (VEGFs) are key regulators of endothelial cell function and angiogenesis. We and others have previously demonstrated that VEGF-A stimulates AMP-activated protein kinase (AMP...

    Authors: James A Reihill, Marie-Ann Ewart and Ian P Salt
    Citation: Vascular Cell 2011 3:9