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  1. Content type: Letter to the Editor

    Angiogenesis is a fundamental process during development and disease, and many details of the underlying molecular and cellular mechanisms are incompletely understood. Mitogen-activated protein kinase (MAPK)-a...

    Authors: L. Christian Napp, Olga Jabs, Anna Höckelmann, Jochen Dutzmann, Piyushkumar R. Kapopara, Daniel G. Sedding, Matthias Gaestel, Johann Bauersachs and Udo Bavendiek

    Citation: Vascular Cell 2016 8:4

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    The Erratum to this article has been published in Vascular Cell 2016 9:1

  2. Content type: Research

    Adipose-derived mesenchymal stromal cells (Ad-MSCs) are a promising tool for advanced cell-based therapies. They are routinely obtained enzymatically from fat lipoaspirate (LP) as SVF, and may undergo prolonged e...

    Authors: Valentina Ceserani, Anna Ferri, Angiola Berenzi, Anna Benetti, Emilio Ciusani, Luisa Pascucci, Cinzia Bazzucchi, Valentina Coccè, Arianna Bonomi, Augusto Pessina, Erica Ghezzi, Offer Zeira, Piero Ceccarelli, Silvia Versari, Carlo Tremolada and Giulio Alessandri

    Citation: Vascular Cell 2016 8:3

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  3. Content type: Research

    Endothelial cells (EC) grown on collagen particles inhibit intimal hyperplasia in animal models when applied perivascularly, and this effect appears to be, at least in part, the result of EC-derived soluble fa...

    Authors: Laura Paneghetti and Yin-Shan Eric Ng

    Citation: Vascular Cell 2016 8:2

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  4. Content type: Case report

    Biological evidence reported in the literature supports the role of CELSR1 as being essential for valvular function in murine lymphatics. Yet thus far, there have been no variants in CELSR1 associated with lympha...

    Authors: M. L. Gonzalez-Garay, M. B. Aldrich, J. C. Rasmussen, R. Guilliod, P. E. Lapinski, P. D. King and E. M. Sevick-Muraca

    Citation: Vascular Cell 2016 8:1

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  5. Content type: Research

    Angiogenesis is essential for uterine decidualization, the progesterone-mediated transformation of the uterus allowing embryo implantation and initiation of pregnancy. In the current study, we define the vascu...

    Authors: Carrie J. Shawber, Lu Lin, Maria Gnarra, Mark V. Sauer, Virginia E. Papaioannou, Jan K. Kitajewski and Nataki C. Douglas

    Citation: Vascular Cell 2015 7:9

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  6. Content type: Review

    Vascular endothelial cells are subjected to hemodynamic forces such as mechanical stretch due to the pulsatile nature of blood flow. Mechanical stretch of different intensities is detected by mechanoreceptors ...

    Authors: Nurul F. Jufri, Abidali Mohamedali, Alberto Avolio and Mark S. Baker

    Citation: Vascular Cell 2015 7:8

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  7. Content type: Research

    Multiple studies demonstrated pro-angiogenic effects of microRNA (miR)-27b. Its targets include Notch ligand Dll4, Sprouty (Spry)-2, PPARγ and Semaphorin (SEMA) 6A. miR-27 effects in the heart are context-depe...

    Authors: Dorina Veliceasa, Dauren Biyashev, Gangjian Qin, Sol Misener, Alexander Roy Mackie, Raj Kishore and Olga V. Volpert

    Citation: Vascular Cell 2015 7:6

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  8. Content type: Research

    (−)-Solenopsin A is a piperidine alkaloid that is a component of the venom of the fire ant Solenopsis invicta. Previously, we have demonstrated that solenopsin exhibit anti-angiogenic activity and downregulate ph...

    Authors: Isabella Karlsson, Xin Zhou, Raquela Thomas, Allorie T Smith, Michael Y Bonner, Pooja Bakshi, Ajay K Banga, J Phillip Bowen, Ghassan Qabaja, Shavon L Ford, Matthew D Ballard, Kimberly S Petersen, Xuechen Li, Guangping Chen, Besim Ogretmen, Jin Zhang…

    Citation: Vascular Cell 2015 7:5

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  9. Content type: Research

    Vascular endothelial growth factor (VEGF) may play a role on the allograft remodelling following cardiac transplantation (CTx). We measured the circulating levels of VEGF-A165 concomitantly with the proinflammato...

    Authors: Damien Vitiello, Diana Chaar, Paul-Eduard Neagoe, Anique Ducharme, Michel Carrier, Guy B Pelletier, Normand Racine, Mark Liszkowski, Martin G Sirois and Michel White

    Citation: Vascular Cell 2015 7:4

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  10. Content type: Research

    Recent evidence suggests that a majority of RNAs in the genome do not code for proteins. They are located in the sense (S) or antisense (AS) orientation and, to date, the functional significance of these non-c...

    Authors: Keguo Li, Tamjid Chowdhury, Padmanabhan Vakeel, Christopher Koceja, Venkatesh Sampath and Ramani Ramchandran

    Citation: Vascular Cell 2015 7:3

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  11. Content type: Research

    Angiogenesis plays a crucial role in development, wound healing as well as tumour growth and metastasis. Although the general implication of the cytoskeleton in angiogenesis has been partially unravelled, litt...

    Authors: Eddy Pasquier, Maria-Pia Tuset, Snega Sinnappan, Michael Carnell, Alexander Macmillan and Maria Kavallaris

    Citation: Vascular Cell 2015 7:2

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  12. Content type: Research

    Therapeutic angiogenesis with vascular endothelial growth factor (VEGF), delivered either via recombinant protein infusion or via gene therapy, has shown promise in preclinical models of various diseases inclu...

    Authors: Eric M George, Huiling Liu, Grant G Robinson, Fakhri Mahdi, Eddie Perkins and Gene L Bidwell III

    Citation: Vascular Cell 2015 7:1

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  13. Content type: Review

    Chronic venous disease (CVD) has a range of clinical presentations, including tortuous, distended veins in lower extremities, increasing skin pigmentation, and in severe cases ulceration of the affected skin. ...

    Authors: Elizabeth S Pocock, Tom Alsaigh, Rafi Mazor and Geert W Schmid-Schönbein

    Citation: Vascular Cell 2014 6:24

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  14. Content type: Review

    Angiogenesis, or the growth of new blood vessels from existing vasculature, is critical for the proper development of many organs. This process is inhibited and tightly regulated in adults, once endothelial ce...

    Authors: Justin Lengfeld, Tyler Cutforth and Dritan Agalliu

    Citation: Vascular Cell 2014 6:23

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  15. Content type: Research

    The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in t...

    Authors: Matthias S Roost, Liesbeth van Iperen, Ana de Melo Bernardo, Christine L Mummery, Françoise Carlotti, Eelco JP de Koning and Susana M Chuva de Sousa Lopes

    Citation: Vascular Cell 2014 6:22

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  16. Content type: Research

    The origins of neointimal smooth muscle cells that arise following vascular injury remains controversial. Studies have suggested that these cells may arise from previously differentiated medial vascular smooth...

    Authors: Brian Paul Herring, April M Hoggatt, Christopher Burlak and Stefan Offermanns

    Citation: Vascular Cell 2014 6:21

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  17. Content type: Research

    Human angiosarcoma and canine hemangiosarcoma are thought to arise from vascular tissue or vascular forming cells based upon their histological appearance. However, recent evidence indicates a hematopoietic or...

    Authors: Brandi H Gorden, Jhuma Saha, Ali Khammanivong, Gary K Schwartz and Erin B Dickerson

    Citation: Vascular Cell 2014 6:20

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  18. Content type: Review

    A decline in the function of the microvasculature occurs with ageing. An impairment of endothelial properties represents a main aspect of age-related microvascular alterations. Endothelial dysfunction manifest...

    Authors: Maria Giovanna Scioli, Alessandra Bielli, Gaetano Arcuri, Amedeo Ferlosio and Augusto Orlandi

    Citation: Vascular Cell 2014 6:19

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  19. Content type: Research

    Lenvatinib is an oral inhibitor of multiple receptor tyrosine kinases (RTKs) targeting vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet growth facto...

    Authors: Yuji Yamamoto, Junji Matsui, Tomohiro Matsushima, Hiroshi Obaishi, Kazuki Miyazaki, Katsuji Nakamura, Osamu Tohyama, Taro Semba, Atsumi Yamaguchi, Sachi Suzuki Hoshi, Fusayo Mimura, Toru Haneda, Yoshio Fukuda, Jun-ichi Kamata, Keiko Takahashi, Masayuki Matsukura…

    Citation: Vascular Cell 2014 6:18

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  20. Content type: Research

    Angiogenesis is an essential process during tumor development and growth. The murine dorsal skinfold window chamber model has been used for the study of both tumor microvasculature and other vascular diseases,...

    Authors: Nikolett M Biel, Jennifer A Lee, Brian S Sorg and Dietmar W Siemann

    Citation: Vascular Cell 2014 6:17

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  21. Content type: Research

    Angiogenesis and macrophage recruitment to the uterus are key features of uterine decidualization; the progesterone-mediated uterine changes that allow for embryo implantation and initiation of pregnancy. In t...

    Authors: Nataki C Douglas, Ralf C Zimmermann, Qian Kun Tan, Chantae S Sullivan-Pyke, Mark V Sauer, Jan K Kitajewski and Carrie J Shawber

    Citation: Vascular Cell 2014 6:16

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  22. Content type: Research

    Magnetite used in an 8-MHz radiofrequency (RF) capacitive heating device can increase the temperature of a specific site up to 45°C. When treating a metastatic lesion around large abdominal vessels via hyperth...

    Authors: Noriyasu Kawai, Daichi Kobayashi, Takahiro Yasui, Yukihiro Umemoto, Kentaro Mizuno, Atsushi Okada, Keiichi Tozawa, Takeshi Kobayashi and Kenjiro Kohri

    Citation: Vascular Cell 2014 6:15

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  23. Content type: Review

    In vitro pre-vascularization is one of the main vascularization strategies in the tissue engineering field. Culturing cells within a tissue-engineered construct (TEC) prior to implantation provides researchers wi...

    Authors: Jeremy Baldwin, Mélanie Antille, Ulrich Bonda, Elena M De-Juan-Pardo, Kiarash Khosrotehrani, Saso Ivanovski, Eugen Bogdan Petcu and Dietmar Werner Hutmacher

    Citation: Vascular Cell 2014 6:13

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  24. Content type: Research

    The majority of triple-negative breast cancers (TNBCs) are basal-like breast cancers. However there is no reported study on anti-tumor effects of sunitinib in xenografts of basal-like TNBC (MDA-MB-468) cells. ...

    Authors: Edmund Chinchar, Kristina L Makey, John Gibson, Fang Chen, Shelby A Cole, Gail C Megason, Srinivassan Vijayakumar, Lucio Miele and Jian-Wei Gu

    Citation: Vascular Cell 2014 6:12

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  25. Content type: Research

    Cyclic RGD peptidomimetics containing a bifunctional diketopiperazine scaffold are a novel class of high-affinity ligands for the integrins αVβ3 and αVβ5. Since integrins are a promising target for the modulation...

    Authors: Roberto Fanelli, Laura Schembri, Umberto Piarulli, Monica Pinoli, Emanuela Rasini, Mayra Paolillo, Marisa Carlotta Galiazzo, Marco Cosentino and Franca Marino

    Citation: Vascular Cell 2014 6:11

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  26. Content type: Research

    Chronic wounds are associated with a number of deficiencies in critical wound healing processes, including growth factor signaling and neovascularization. Human-derived placental tissues are rich in regenerati...

    Authors: Thomas J Koob, Jeremy J Lim, Michelle Massee, Nicole Zabek, Robert Rennert, Geoffrey Gurtner and William W Li

    Citation: Vascular Cell 2014 6:10

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  27. Content type: Research

    Dicer is an RNase III enzyme that cleaves double stranded RNA and generates functional interfering RNAs that act as important regulators of gene and protein expression. Dicer plays an essential role during mou...

    Authors: Sébastien Gauvrit, Josette Philippe, Matthieu Lesage, Marc Tjwa, Isabelle Godin and Stéphane Germain

    Citation: Vascular Cell 2014 6:9

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  28. Content type: Methodology

    The understanding of endothelial cell biology has been facilitated by the availability of primary endothelial cell cultures from a variety of sites and species; however, the isolation and maintenance of primar...

    Authors: Chih-Wen Ni, Sandeep Kumar, Casey J Ankeny and Hanjoong Jo

    Citation: Vascular Cell 2014 6:7

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  29. Content type: Research

    The A10 and A7r5 cell lines derived from the thoracic aorta of embryonic rat are widely used as models of non-differentiated, neonatal and neointimal vascular smooth muscle cells in culture. The recent discove...

    Authors: Eimear Kennedy, Roya Hakimjavadi, Chris Greene, Ciaran J Mooney, Emma Fitzpatrick, Laura E Collins, Christine E Loscher, Shaunta Guha, David Morrow, Eileen M Redmond and Paul A Cahill

    Citation: Vascular Cell 2014 6:6

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  30. Content type: Review

    Macrophages are highly plastic hematopoietic cells with diversified functions related to their anatomic location and differentiation states. A number of recent studies have examined the role of macrophages in ...

    Authors: Xinguo Jiang, Wen Tian, Yon K Sung, Jin Qian and Mark R Nicolls

    Citation: Vascular Cell 2014 6:5

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  31. Content type: Research

    The overexpression of angiopoietin-2 (Ang-2) has both pro-tumorigenic and anti-tumorigenic effects. However, the mechanisms of this protein’s dual effects are poorly understood, and it remains unclear how Ang-...

    Authors: Hai-Hong Chen, Bin-Qi Weng, Ke-Jia Cheng, Hong-Yan Liu, Shen-Qing Wang and Yv-Yv Lu

    Citation: Vascular Cell 2014 6:4

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  32. Content type: Research

    Eribulin mesylate is a synthetic macrocyclic ketone analog of the marine sponge natural product halichondrin B. Eribulin is a tubulin-binding drug and approved in many countries worldwide for treatment of cert...

    Authors: Sergei I Agoulnik, Satoshi Kawano, Noel Taylor, Judith Oestreicher, Junji Matsui, Jesse Chow, Yoshiya Oda and Yasuhiro Funahashi

    Citation: Vascular Cell 2014 6:3

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  33. Content type: Research

    Netrins are secreted molecules involved in axon guidance and angiogenesis. We previously showed that Netrin-4 acts as an anti-angiogenic factor by inhibiting endothelial cell (EC) functions. In this study, we ...

    Authors: Esma Lejmi, Ilyes Bouras, Serge Camelo, Marie Roumieux, Norbert Minet, Carole Leré-Déan, Tatyana Merkulova-Rainon, Gwennhael Autret, Catherine Vayssettes, Olivier Clement, Jean Plouët and Laurence Leconte

    Citation: Vascular Cell 2014 6:1

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  34. Content type: Review

    Tumor vascularization is a highly complex process that involves the interaction between tumors and their surrounding stroma, as well as many distinct angiogenesis-regulating factors. Tumor associated macrophag...

    Authors: Chunqing Guo, Annicole Buranych, Devanand Sarkar, Paul B Fisher and Xiang-Yang Wang

    Citation: Vascular Cell 2013 5:20

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    The Erratum to this article has been published in Vascular Cell 2014 6:2

  35. Content type: Review

    The average human body contains tens of thousands of miles of vessels that permeate every tissue down to the microscopic level. This makes the human vasculature a prime target for an agent like radiation that ...

    Authors: Peter Grabham and Preety Sharma

    Citation: Vascular Cell 2013 5:19

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  36. Content type: Research

    Polycystic ovarian syndrome (PCOS) ovaries are characterized by increased angiogenesis and hypervascularity. While angiopoietin-1 (Ang-1) and its antagonist, angiopoietin-2 (Ang-2), are essential for ovarian f...

    Authors: Reshef Tal, David B Seifer, Richard V Grazi and Henry E Malter

    Citation: Vascular Cell 2013 5:18

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  37. Content type: Research

    Anti-angiogenesis is a validated strategy to treat cancer, with efficacy in controlling both primary tumor growth and metastasis. The role of the Notch family of proteins in tumor angiogenesis is still emergin...

    Authors: Sonia L Hernandez, Debarshi Banerjee, Alejandro Garcia, Thaned Kangsamaksin, Wei-Yi Cheng, Dimitris Anastassiou, Yasuhiro Funahashi, Angela Kadenhe-Chiweshe, Carrie J Shawber, Jan K Kitajewski, Jessica J Kandel and Darrell J Yamashiro

    Citation: Vascular Cell 2013 5:17

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  38. Content type: Research

    The heterodimeric, oxygen-sensitive transcription factor Hypoxia Inducible Factor-1 (HIF-1) orchestrates angiogenesis and plays a key role in the response to ischemia and the growth of cancers.

    Authors: Chad B Walton, Jennifer Ecker, Cynthia D Anderson, Joel T Outten, Randall Z Allison and Ralph V Shohet

    Citation: Vascular Cell 2013 5:15

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  39. Content type: Research

    Gene therapy stimulating the growth of blood vessels is considered for the treatment of peripheral and myocardial ischemia. Here we aimed to achieve angiogenic synergism between vascular endothelial growth fac...

    Authors: Agnieszka Jazwa, Mateusz Tomczyk, Hevidar M Taha, Elisa Hytonen, Mateusz Stoszko, Lorena Zentilin, Mauro Giacca, Seppo Yla-Herttuala, Costanza Emanueli, Alicja Jozkowicz and Jozef Dulak

    Citation: Vascular Cell 2013 5:13

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  40. Content type: Erratum

    After the publication of this work [1] it was brought to our attention that citations in the article were not correspondingly numbered in the reference list. To avoid confusion, the article is republished here in...

    Authors: Tom Arnold and Christer Betsholtz

    Citation: Vascular Cell 2013 5:12

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    The original article was published in Vascular Cell 2013 5:4

  41. Content type: Review

    Angiogenesis plays a key role in several rheumatic diseases, including rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, systemic sclerosis, systemic lupus erythematosus, and vasculitides. An imbal...

    Authors: Nicola Maruotti, Tiziana Annese, Francesco Paolo Cantatore and Domenico Ribatti

    Citation: Vascular Cell 2013 5:11

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  42. Content type: Research

    Brain microvascular endothelial cells (BMVECs) constitute the primary limitation for passage of ions and molecules from the blood into the brain through the blood brain barrier. Numerous multi-step procedures ...

    Authors: Stefania Elena Navone, Giovanni Marfia, Sara Nava, Gloria Invernici, Silvia Cristini, Sergio Balbi, Simone Sangiorgi, Emilio Ciusani, Alessandra Bosutti, Giulio Alessandri, Mark Slevin and Eugenio Agostino Parati

    Citation: Vascular Cell 2013 5:10

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