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  1. Letter to the Editor

    Normal endothelial but impaired arterial development in MAP-Kinase activated protein kinase 2 (MK2) deficient mice

    Angiogenesis is a fundamental process during development and disease, and many details of the underlying molecular and cellular mechanisms are incompletely understood. Mitogen-activated protein kinase (MAPK)-a...

    L. Christian Napp, Olga Jabs, Anna Höckelmann, Jochen Dutzmann, Piyushkumar R. Kapopara, Daniel G. Sedding, Matthias Gaestel, Johann Bauersachs and Udo Bavendiek

    Vascular Cell 2016 8:4

    Published on: 21 October 2016

    The Erratum to this article has been published in Vascular Cell 2016 9:1

  2. Research

    Angiogenic and anti-inflammatory properties of micro-fragmented fat tissue and its derived mesenchymal stromal cells

    Adipose-derived mesenchymal stromal cells (Ad-MSCs) are a promising tool for advanced cell-based therapies. They are routinely obtained enzymatically from fat lipoaspirate (LP) as SVF, and may undergo prolonged e...

    Valentina Ceserani, Anna Ferri, Angiola Berenzi, Anna Benetti, Emilio Ciusani, Luisa Pascucci, Cinzia Bazzucchi, Valentina Coccè, Arianna Bonomi, Augusto Pessina, Erica Ghezzi, Offer Zeira, Piero Ceccarelli, Silvia Versari, Carlo Tremolada and Giulio Alessandri

    Vascular Cell 2016 8:3

    Published on: 18 August 2016

  3. Case report

    A novel mutation in CELSR1 is associated with hereditary lymphedema

    Biological evidence reported in the literature supports the role of CELSR1 as being essential for valvular function in murine lymphatics. Yet thus far, there have been no variants in CELSR1 associated with lympha...

    M. L. Gonzalez-Garay, M. B. Aldrich, J. C. Rasmussen, R. Guilliod, P. E. Lapinski, P. D. King and E. M. Sevick-Muraca

    Vascular Cell 2016 8:1

    Published on: 5 February 2016

  4. Research

    Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus

    Angiogenesis is essential for uterine decidualization, the progesterone-mediated transformation of the uterus allowing embryo implantation and initiation of pregnancy. In the current study, we define the vascu...

    Carrie J. Shawber, Lu Lin, Maria Gnarra, Mark V. Sauer, Virginia E. Papaioannou, Jan K. Kitajewski and Nataki C. Douglas

    Vascular Cell 2015 7:9

    Published on: 1 December 2015

  5. Research

    Therapeutic manipulation of angiogenesis with miR-27b

    Multiple studies demonstrated pro-angiogenic effects of microRNA (miR)-27b. Its targets include Notch ligand Dll4, Sprouty (Spry)-2, PPARγ and Semaphorin (SEMA) 6A. miR-27 effects in the heart are context-depe...

    Dorina Veliceasa, Dauren Biyashev, Gangjian Qin, Sol Misener, Alexander Roy Mackie, Raj Kishore and Olga V. Volpert

    Vascular Cell 2015 7:6

    Published on: 24 June 2015

  6. Research

    Solenopsin A and analogs exhibit ceramide-like biological activity

    (−)-Solenopsin A is a piperidine alkaloid that is a component of the venom of the fire ant Solenopsis invicta. Previously, we have demonstrated that solenopsin exhibit anti-angiogenic activity and downregulate ph...

    Isabella Karlsson, Xin Zhou, Raquela Thomas, Allorie T Smith, Michael Y Bonner, Pooja Bakshi, Ajay K Banga, J Phillip Bowen, Ghassan Qabaja, Shavon L Ford, Matthew D Ballard, Kimberly S Petersen, Xuechen Li, Guangping Chen, Besim Ogretmen, Jin Zhang…

    Vascular Cell 2015 7:5

    Published on: 8 May 2015

  7. Research

    Decreased circulating and neutrophil mediated VEGF-A165 release in stable long-term cardiac transplant recipients

    Vascular endothelial growth factor (VEGF) may play a role on the allograft remodelling following cardiac transplantation (CTx). We measured the circulating levels of VEGF-A165 concomitantly with the proinflammato...

    Damien Vitiello, Diana Chaar, Paul-Eduard Neagoe, Anique Ducharme, Michel Carrier, Guy B Pelletier, Normand Racine, Mark Liszkowski, Martin G Sirois and Michel White

    Vascular Cell 2015 7:4

    Published on: 22 April 2015

  8. Research

    Delta-like 4 mRNA is regulated by adjacent natural antisense transcripts

    Recent evidence suggests that a majority of RNAs in the genome do not code for proteins. They are located in the sense (S) or antisense (AS) orientation and, to date, the functional significance of these non-c...

    Keguo Li, Tamjid Chowdhury, Padmanabhan Vakeel, Christopher Koceja, Venkatesh Sampath and Ramani Ramchandran

    Vascular Cell 2015 7:3

    Published on: 24 March 2015

  9. Research

    γ-Actin plays a key role in endothelial cell motility and neovessel maintenance

    Angiogenesis plays a crucial role in development, wound healing as well as tumour growth and metastasis. Although the general implication of the cytoskeleton in angiogenesis has been partially unravelled, litt...

    Eddy Pasquier, Maria-Pia Tuset, Snega Sinnappan, Michael Carnell, Alexander Macmillan and Maria Kavallaris

    Vascular Cell 2015 7:2

    Published on: 6 February 2015

  10. Review

    Cellular and molecular basis of Venous insufficiency

    Chronic venous disease (CVD) has a range of clinical presentations, including tortuous, distended veins in lower extremities, increasing skin pigmentation, and in severe cases ulceration of the affected skin. ...

    Elizabeth S Pocock, Tom Alsaigh, Rafi Mazor and Geert W Schmid-Schönbein

    Vascular Cell 2014 6:24

    Published on: 12 December 2014

  11. Review

    The role of angiogenesis in the pathology of multiple sclerosis

    Angiogenesis, or the growth of new blood vessels from existing vasculature, is critical for the proper development of many organs. This process is inhibited and tightly regulated in adults, once endothelial ce...

    Justin Lengfeld, Tyler Cutforth and Dritan Agalliu

    Vascular Cell 2014 6:23

    Published on: 28 November 2014

  12. Research

    Lymphangiogenesis and angiogenesis during human fetal pancreas development

    The complex endocrine and exocrine functionality of the human pancreas depends on an efficient fluid transport through the blood and the lymphatic vascular systems. The lymphatic vasculature has key roles in t...

    Matthias S Roost, Liesbeth van Iperen, Ana de Melo Bernardo, Christine L Mummery, Françoise Carlotti, Eelco JP de Koning and Susana M Chuva de Sousa Lopes

    Vascular Cell 2014 6:22

    Published on: 1 November 2014

  13. Review

    Ageing and microvasculature

    A decline in the function of the microvasculature occurs with ageing. An impairment of endothelial properties represents a main aspect of age-related microvascular alterations. Endothelial dysfunction manifest...

    Maria Giovanna Scioli, Alessandra Bielli, Gaetano Arcuri, Amedeo Ferlosio and Augusto Orlandi

    Vascular Cell 2014 6:19

    Published on: 16 September 2014

  14. Research

    Lenvatinib, an angiogenesis inhibitor targeting VEGFR/FGFR, shows broad antitumor activity in human tumor xenograft models associated with microvessel density and pericyte coverage

    Lenvatinib is an oral inhibitor of multiple receptor tyrosine kinases (RTKs) targeting vascular endothelial growth factor receptor (VEGFR1-3), fibroblast growth factor receptor (FGFR1-4), platelet growth facto...

    Yuji Yamamoto, Junji Matsui, Tomohiro Matsushima, Hiroshi Obaishi, Kazuki Miyazaki, Katsuji Nakamura, Osamu Tohyama, Taro Semba, Atsumi Yamaguchi, Sachi Suzuki Hoshi, Fusayo Mimura, Toru Haneda, Yoshio Fukuda, Jun-ichi Kamata, Keiko Takahashi, Masayuki Matsukura…

    Vascular Cell 2014 6:18

    Published on: 6 September 2014

  15. Research

    VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment

    Angiogenesis and macrophage recruitment to the uterus are key features of uterine decidualization; the progesterone-mediated uterine changes that allow for embryo implantation and initiation of pregnancy. In t...

    Nataki C Douglas, Ralf C Zimmermann, Qian Kun Tan, Chantae S Sullivan-Pyke, Mark V Sauer, Jan K Kitajewski and Carrie J Shawber

    Vascular Cell 2014 6:16

    Published on: 1 August 2014

  16. Research

    Evaluation of side effects of radiofrequency capacitive hyperthermia with magnetite on the blood vessel walls of tumor metastatic lesion surrounding the abdominal large vessels: an agar phantom study

    Magnetite used in an 8-MHz radiofrequency (RF) capacitive heating device can increase the temperature of a specific site up to 45°C. When treating a metastatic lesion around large abdominal vessels via hyperth...

    Noriyasu Kawai, Daichi Kobayashi, Takahiro Yasui, Yukihiro Umemoto, Kentaro Mizuno, Atsushi Okada, Keiichi Tozawa, Takeshi Kobayashi and Kenjiro Kohri

    Vascular Cell 2014 6:15

    Published on: 15 July 2014

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