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Fig. 3 | Vascular Cell

Fig. 3

From: Vascular Notch proteins and Notch signaling in the peri-implantation mouse uterus

Fig. 3

Distribution of endothelial cells and patent vessels identified by FITC-dextran in the post-implantation uterus. H&E, IHC and fluorescently labeled dextran in E6.5 uterine sections. (A) H&E at E6.5 highlighting the embryo (e) and inter-implantation sites (i). (B) CD31+ ECs are abundant in the decidua and myometrium. (C) H&E at E6.5 highlighting the embryo surrounded by blood filled maternal sinusoids (box 1, C1) and the blood filled lateral vascular sinuses in the mesometrial decidua (box 2, C2). (D) FITC-dextran is detected in capillaries (D3, arrow) and has extravasated into sinusoids around the embryo (D1), lateral vascular sinuses in the mesometrial decidua (D2 and D3, arrowhead), and the stroma (D3, asterisk). DAPI identifies all nuclei in IF images. am, anti-mesometrial; m, mesometrial; s, serosa. Bar in A and B = 100 μm. Bar in C and D = 500 μm. Bar in A1 and B1, C1, C2, D1 – D3 = 50 μm.

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