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Table 4 Cyclic mechanical stretch affects differentiation in VSMCs in vitro

From: Variability in vascular smooth muscle cell stretch-induced responses in 2D culture

Study Cell type Freq. Unit Stretch Plate Axis Time Wave Results
Yao [51] AoSMC (rat) 1.25 Hz FX-4000 10 % Gelatin Equibiaxial 24 h   Differentiation ↑
Turczynska [17] Mouse portal vein   0.3 g weight     5 min   Differentiation ↑
Hu [46] AoSMC (human) 1 Hz FX-5000 16 % Collagen I   0–30 min   Differentiation ↓
Butcher [45] AoSMC (rat) 1 Hz Custom 10 % Collagen I, Fibronectin, Cel-tak Equibiaxial 48 h Sinusoidal Differentiation ↓
Wan [48] AoSMC (rat) 1.25 Hz FX-4000 5 %, 15 % Collagen I   24 h   Differentiation ↓
Rodriguez [47] AoSMC (rat) 1 Hz FX-5000 10 % Collagen I Uniaxial 0–24 h Sinusoidal Differentiation ↓
Song [31] Venous VSMC (rat) 1 Hz Custom     0–24 h   Differentiation ↑