Figure 1
From: Delta-like 4 mRNA is regulated by adjacent natural antisense transcripts
Identification of Dll4-AS isoforms. (A) RACE reactions mapped the Dll4-AS into Dll4 promoter region. Blue and red arrowheads indicate transcriptional orientations of Dll4-AS and Dll4, respectively. Horizontal black arrowheads indicate following primers’ locations. Vertical black and grey arrows indicate following siRNA and miRNA targets, respectively. (B) Dll4-AS is enriched in cellular cytoplasm. (C) Dll4-AS expression coincides with Dll4 in different cell lines. Bend.3: mouse endothelial cell from cerebral cortex; EOMA: mouse endothelial cell from hemangioendothelioma; MAE: Mouse Aortic Endothelial cell; MBE: Mouse Brain capillary Endothelial cell; MS1: mouse endothelial cell from pancreas; sMHEC: Mouse Heart Endothelial Cells.