Figure 2
From: Lymphangiogenesis and angiogenesis during human fetal pancreas development
Blood vessels and their association with smooth muscle cells and basement membrane formation during human pancreatic development. (A) Pancreata at W9, W11, W12 and W19 immunostained for CD31 and smooth muscle actin (ACTA2). Smooth muscle cell association with blood vessels in the peri-pancreatic mesenchyme (PPM, top panels) and intra-pancreatic mesenchyme (IPM, bottom panels) is shown. (B) Pancreas at W9 immunostained for CD31 and collagen type IV (COL4A) illustrating blood vessels in the PPM (top panels) and IPM (bottom panels). White arrows point to CD31-positive blood vessels with a continuous basement membrane. Note that autofluorescent red blood cells, as yellow/orange dots, are present in in all images. Scale bars: 30 μm.