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Figure 5 | Vascular Cell

Figure 5

From: The role of AMP-activated protein kinase in the functional effects of vascular endothelial growth factor-A and -B in human aortic endothelial cells

Figure 5

AMPK is required for VEGF-A-stimulated migration. A) HAECs were infected with Ad.control, Ad.AMPK-DN or Ad.AMPK-CA for 24 h prior to assessment of migration in response to 10 ng/ml VEGF-A or 100 ng/ml VEGF-B using a Boyden chamber. B) HAECs were incubated in the presence or absence of L-NAME (1 mM) 60 min prior to incubation with VEGF-A (10 ng/ml) for 24 h and migration assessed. The results are expressed as the mean ± SEM% VEGF-stimulated migration for three independent experiments. *p < 0.001 relative to absence of VEGF, ** p < 0.001 relative to Ad.control-infected cells.

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Vascular Cell

ISSN: 2045-824X

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