Table 2 Effects of strain on VSMC intracellular signaling.
From: Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells
MEK1/ERK | PKC | CDK | |||
|---|---|---|---|---|---|
Protein | %CFC | Protein | %CFC | Protein | %CFC |
MEK1 | +148% | PKC λ/ι | +41.4% | Cdk4 | -26% |
MEK1T385 | +68.1% | PKC λ/ιT555 | +90.3% | Cdk6 | -39.3% |
MEK1T291 | +159% | PKC ζ | +87% | Cdk1/2T14+Y15 | -50% |
MEK1S298 | +62% | PKC θ | +231% | Cdk2 | -49.6% |
MEK2 | +188.1% | PKC θS695 | +44.6% |  |  |
ERKT202+Y204/T185+Y187 | +130% | PKC μ | +97.3% |  |  |
|  |  | PKC ε | +30% |  |  |
|  |  | PKC δ | +40.5% |  |  |