Figure 3
From: Angiogenesis in old-aged subjects after ischemic stroke: a cautionary note for investigators
Possible molecular mechanisms and general effects of angiogenesis after stroke in elderly subjects. Stroke causes ischemic damage to the brain, activating angiogeneic mechanisms in response. The degree of response is modulated by changes to the neural and vascular response caused by aging, but the general response remains similar. Growth factors, tissue remodeling and inflammatory proteins are released, leading to the building of new, well developed endothelial channels, which aid recovery.