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Fig. 6 | Vascular Cell

Fig. 6

From: A novel endothelial-derived anti-inflammatory activity significantly inhibits spontaneous choroidal neovascularisation in a mouse model

Fig. 6

a Dose-dependent anti-inflammatory effects of ECPCM. HAEC were treated for 2 h with TNFα in collection medium, ECPCM, or serial dilutions (1:2) of ECPCM in collection medium. The graph shows the percentage of expression of E-selectin and VCAM-1 relative to that observed for TNFα in collection medium, as determined by real-time PCR analysis. Data = mean ± SEM. b ECPCM anti-inflammatory activity is not affected by proteinase K or RNase treatment. Gene expression of E-selectin and VCAM-1 was analysed by real-time PCR after treatment for 2 h with TNFα. HAEC were treated with collection medium, ECPCM or ECPCM previously treated with proteinase K or RNase. p value: * <0.001 compared to treatment with TNFα in collection medium. Data = mean ± SEM

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Vascular Cell

ISSN: 2045-824X

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