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Table 5 Cyclic mechanical stretch affects secretion of MMP-2 in VSMCs in vitro

From: Variability in vascular smooth muscle cell stretch-induced responses in 2D culture

Study

Cell type

Freq.

Unit

Stretch

Plate

Axis

Time

Wave

Results

Seo [67]

AoSMC (rat)

1 Hz

FX-4000

0–10 %

Pronectin

 

0–12 h

 

MMP-2 ↑

Yamashita [68]

AoSMC (rat)

0.5 Hz

STREX

2 %, 5 %, 20 %

Laminin

Uniaxial

48 h

 

MMP-2 ↑

Grote [69]

AoSMC (mouse)

0.5 Hz

FX-3000

15 %

Collagen I

 

0–24 h

 

MMP-2 ↑