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Table 5 Cyclic mechanical stretch affects secretion of MMP-2 in VSMCs in vitro

From: Variability in vascular smooth muscle cell stretch-induced responses in 2D culture

Study Cell type Freq. Unit Stretch Plate Axis Time Wave Results
Seo [67] AoSMC (rat) 1 Hz FX-4000 0–10 % Pronectin   0–12 h   MMP-2 ↑
Yamashita [68] AoSMC (rat) 0.5 Hz STREX 2 %, 5 %, 20 % Laminin Uniaxial 48 h   MMP-2 ↑
Grote [69] AoSMC (mouse) 0.5 Hz FX-3000 15 % Collagen I   0–24 h   MMP-2 ↑