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Table 2 Cyclic mechanical stretch affects proliferation in VSMCs in vitro

From: Variability in vascular smooth muscle cell stretch-induced responses in 2D culture

Study Cell type Freq. Unit Stretch Plate Axis Time Wave Results
Standley [59] AoSMC (rat) 1 Hz Flexercell 20 % Collagen I Uniaxial 48 h   Proliferation ↑
Li [61] AoSMC (bovine) 1 Hz FX-4000 10 % Collagen I   0–24 h Square Proliferation ↑
Chahine [24] AoSMC (rabbit) 1 Hz FX-4000 20 %    48 h   Proliferation ↑
Chang [23] AoSMC (rat) 1 Hz FX-2000 20 %    0–24 h Sinusoidal Proliferation ↑
Liu [27] AoSMC (rat) 1 Hz Flexercell 5 %, 15 % Collagen I   2 h   Proliferation ↑
Liu [25] AoSMC (mouse) 1 Hz FX-3000 0–25 %    0–60 min   Proliferation ↑
Mata-Greenwood [22] PASMC (sheep) 1 Hz FX-4000 20 % Collagen I Biaxial 0–24 h   Proliferation ↑
Song [31] Venous VSMC (rat) 1 Hz Custom     0–24 h   Proliferation ↑
Song [32] AoSMC (human) 1 Hz FX-5000 10 %, 16 % Collagen I   0–24 h   Proliferation ↑
Morrow [29] VSMC (rat) 1 Hz FX-4000 0–15 %    0–24 h Heart(P) Proliferation ↓
Guha [28] VSMC (rat) 1 Hz FX-4000 0–10 % Pronectin   0–24 h Heart(P) Proliferation ↓