Parameters
|
CAV (
n
= 7)
|
No CAV (
n
= 11)
|
---|
Biomarkers
| | |
VEGF-A165
|
63.3 ± 27.8
|
48.4 ± 15.1
|
IL-8
|
6.20 ± 1.59
|
3.61 ± 0.74
|
IL-RA
|
331 ± 99
|
187 ± 30
|
Neutrophils/Factors
| | |
VEGF release
| | |
PBS
|
10.5 ± 2.8
|
11.7 ± 1.9
|
fMLP
|
47.1 ± 9.5
|
52.7 ± 9.3
|
LPS
|
33.4 ± 5.5
|
46.7 ± 8.9
|
TNF-α
|
51.7 ± 11.4
|
60.7 ± 10.6
|
IL-8 release
| | |
PBS
|
23.7 ± 5.3
|
14.7 ± 2.8
|
fMLP
|
115 ± 19
|
161 ± 20
|
LPS
|
1100 ± 115
|
1180 ± 67
|
TNF-α
|
728 ± 81
|
898 ± 76
|
IL-1RA release
| | |
PBS
|
187 ± 43
|
229 ± 44
|
fMLP
|
178 ± 43
|
248 ± 42
|
LPS
|
253 ± 52
|
357 ± 54
|
TNF-α
|
457 ± 66
|
515 ± 55
|
- CAV: Cardiac allograft vasculopathy; VEGF: Vascular endothelial growth factor; IL: Interleukin; RA: Receptor antagonist; PBS: Vehicule; fMLP: N-formyl-Met-Leu-Phe; LPS: Bacterial lipopolysaccharides; TNF: Tumor necrosis factor. Variables are expressed as mean ± SEM and percentages.