Figure 1
From: The role of RNA interference in the developmental separation of blood and lymphatic vasculature
Conditional deletion of dicer gene leads to hemorrhage and edema. A) Whole-mount view of WT and dicerΔEC/ΔEC embryos from E12.5 to E14.5. Hemorrhagic regions and edema are indicated (arrows). Scale Bar: 500 μm. B) PCR genotyping analysis of PECAM+ endothelial cells from E13.5 dicerΔEC/+ and dicerΔEC/ΔEC embryos. Detection of Cre and dicer fragments (floxed, excised and WT) are presented.