Skip to main content
Figure 4 | Vascular Cell

Figure 4

From: Previously differentiated medial vascular smooth muscle cells contribute to neointima formation following vascular injury

Figure 4

Myh11 expression is down-regulated 7 days following injury. 5-week old male Myh11 creER(T2)-/+ mTmG-/+ mice were treated with tamoxifen (1 mg,IP) once a day for 5 days. Two weeks following the last tamoxifen injection the left carotid artery was ligated and tissues were harvested 7 days later. 8 μm cryosections obtained from injured and contralateral control arteries were analyzed for expression of myh11 (using an anti-SM2 antibody) (red) and mEGFP (green) and mTomato (white). Control and injured sections are shown at identical exposures. Images shown are representative of those obtained from 3 different mice. In the lower panels the SM2 antibody was omitted and the samples otherwise processed identically to those shown in the upper panels. All images are shown at the same magnification with the scale bar shown in the bottom left panel representing 50 μm.

Back to article page

Vascular Cell

ISSN: 2045-824X

Contact us