Figure 10

Acta2 -tagged medial SMCs give rise to the neointima following carotid ligation. Control and injured carotid arteries from Tamoxifen (TAM) or corn oil (CO) treated Acta2 creER(T2)-/+ mTmG-/+ transgenic mice harvested 28 days post ligation (Mice numbers 11, 12 and 13, respectively; Table 1). Images from tamoxifen treated injured vessels are representative of those obtained from 7 mice.