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Figure 6 | Vascular Cell

Figure 6

From: Lysosomal drug sequestration as a mechanism of drug resistance in vascular sarcoma cells marked by high CSF-1R expression

Figure 6

CSF-1Rhighcells show increased retention of doxorubicin. COSB cells were incubated with 1 μM doxorubicin and the levels of doxorubicin and CSF-1R expression were measured by flow cytometry immediately after incubation (t = 0) and 24 hours later (t = 24). The levels of doxorubicin were significantly higher in the CSF-1Rhigh cells than in the CSF-1Rlow cells at t = 0 (p = 0.005) and t = 24 hours (p = 0.03).

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Vascular Cell

ISSN: 2045-824X

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