Figure 4From: Limitations of the dorsal skinfold window chamber model in evaluating anti-angiogenic therapy during early phase of angiogenesisAng-2 inhibition in Caki-2 cell induced angiogenesis. Mice bearing window chambers with Caki-2 tumors were treated with Ang-2 inhibitor (monoclonal antibody). (A) Tumor volume and (B) tumor microvascular response to the Ang-2 inhibitor was evaluated compared to control. Median + 90/10 percentile; control (n = 8), anti-Ang-2 (n = 7) (combination of two independent experiments).Back to article page