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Table 1 Effect of anti-VEGFR-1 blocking antibody MF-1 on pregnancy, decidual macrophages and vascular density

From: VEGFR-1 blockade disrupts peri-implantation decidual angiogenesis and macrophage recruitment

 

Anti-VEGFR-1 (MF-1)

Control

 

E7.5

E10.5

E7.5

E10.5

Implantation sites (#)

13 ± 0.6

12.1 ± 0.4

13 ± 0.3

11.8 ± 0.9

Uterine weights (g)

0.35 ± 0.01

2.1 ± 0.1

0.36 ± 0.02

2.3 ± 0.1

Serum progesterone (ng/mL)

23.4 ± 2.3

 

27.9 ± 1.1

 

Macrophage density

6.7 × 10-5 ± 1.1 × 10-6a

 

2.5 × 10-5 ± 4.3 × 10-7a

 

Vascular density

13.1 ± 0.2b

 

6.3 ± 0.2b

 
  1. a, bP < 0.01.
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Vascular Cell

ISSN: 2045-824X

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