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Figure 1 | Vascular Cell

Figure 1

From: EGCG, a major green tea catechin suppresses breast tumor angiogenesis and growth via inhibiting the activation of HIF-1α and NFκB, and VEGF expression

Figure 1

The inhibition of the progression of breast cancer growth by oral EGCG in the immunocompetant female mice (C57BL/6) allografted with mouse breast cancer (E0771) cells. EGCG at 50 to 100 mg/kg/day in drinking water for four weeks significantly reduced a growth curve of breast cancer monitored by the tumor cross section area by 65% (Figure 1A, P < 0.01; n = 8) and tumor weight (Figure 1B, 0.37 ± 0.15 vs. 1.16 ± 0.30 g; P < 0.01; n = 8), compared to the control group.

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