Figure 3
From: Cardiac angiogenesis directed by stable Hypoxia Inducible Factor-1
Myocardial vascular leakage following stable transgene induction for up to ten days. Vascular leakage was evaluated by perfusion with Evans Blue dye via left ventricular injection, and subsequent dye extravasation quantified by absorbance analysis. Even with an increased heart weight (HW) to body weight (BW) ratio, there is no increase in dye release, suggesting the newly formed capillary sized vessels are indeed functional. (n=6 for each analysis). (** denotes p<0.01).