Figure 2
From: Nanotechnology-mediated targeting of tumor angiogenesis
Effects of LY-encapsulated PLGA nanoparticles in vivo using Casper Zebrafish-breast adenocarcinoma xenograft assay. (A) Real-time imaging. Broken arrows show cancer cells. (B) Alkaline phosphatase vessel staining. Full arrows show subintestinal vessels (SIV). (C) Quantification of SIV using morphometric analyses developed in our laboratory. HNP = hybrid nanoparticles. P# ≤ 0.05 versus wild-type and empty nanoparticle controls. (In collaboration with Dr. Richard M. White and Dr. Leonard I. Zon, Children's Hospital Boston).