Skip to main content

Table 1 Types of VEGFR and VEGF

From: Nanoparticle mediated targeting of VEGFR and cancer stem cells for cancer therapy

Type of VEGFR

Binds to

Location of expression

Reference

VEGFR-1

VEGF-A, VEGF-B, P1GF

Thymus, monocytes, macrophages, dendritic cells, osteoclast, astrocytes

[5–8]

VEGFR-2

VEGF-A, VEGF-B, VEGF-C, VEGF-D

Vascular endothelial progenitors cells, heamatopioetic stem cells, Neuronal cells, osteoblasts, osteoclast, pancreatic duct cells, retinal progenitor cells, megakaryocytes

[9–11]

VEGFR-3

VEGF-C, VEGF-D

Lymphatic endothelial cells, capillaries and veins in endocrine organs, monocytes and macrophages, neural progenitor cells

[12, 13]