From: Nanoparticle mediated targeting of VEGFR and cancer stem cells for cancer therapy
Type of VEGFR | Binds to | Location of expression | Reference |
---|---|---|---|
VEGFR-1 | VEGF-A, VEGF-B, P1GF | Thymus, monocytes, macrophages, dendritic cells, osteoclast, astrocytes | |
VEGFR-2 | VEGF-A, VEGF-B, VEGF-C, VEGF-D | Vascular endothelial progenitors cells, heamatopioetic stem cells, Neuronal cells, osteoblasts, osteoclast, pancreatic duct cells, retinal progenitor cells, megakaryocytes | |
VEGFR-3 | VEGF-C, VEGF-D | Lymphatic endothelial cells, capillaries and veins in endocrine organs, monocytes and macrophages, neural progenitor cells |