Figure 4
From: Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells
Effects of Strain on VEGF Secretion and VEGF Blockade on VSMC Proliferation: (A) Temporal changes in VEGF secretion from control (open symbols) and strained VSMC. N = 5 per group; * p ≤ 0.05 vs. control at same time point. (B) Lack of significant effects of 18 hours (closed symbols) and 48 hours (open symbols) of exogenous VEGF treatment on proliferation in unstrained VSMC (N = 9). (C) Effects of strain (closed bars) and anti-VEGF treatment on VSMC proliferation. N = 6; *p < 0.05 vs strain only group; **p < 0.01 vs strain only group.