Figure 3
From: Cyclic strain upregulates VEGF and attenuates proliferation of vascular smooth muscle cells
Strain Regulation of VSMC Cytokine Secretion: Changes in cytokine levels in conditioned media from control and strained VSMC. (A) Representative matched protein microarrays from control (left) and strained (right) groups. VEGF signals have been enlarged for clarity. (B) Summary data for six protein microarrays showing percent change from control in cytokine levels *p < 0.05 vs. %CFC > 25%; #p < 0.05 vs. %CFC > 50%. All data are corrected on a per-cell basis. CINC-2 (cytokine induced neutrophil chemoattractant-2), CINC-3 (cytokine induced neutrophil chemoattractant-3), CNTF (ciliary neuronotrophic factor), GM-CSF (granulocyte-macrophage colony stimulating factor), IFN-γ (interferon-γ), LIX (lipopolysaccharide-induced CXC chemokine), MCP-1 (monocyte chemotactic protein-1), MIP-3α (macrophage inflammatory protein-3-alpha), β-NGF (beta-nerve growth factor), TIMP-1 (tissue inhibitor of metalloproteinases), TNF-α (tumor necrosis factor α), and VEGF (Vascular Endothelial Growth Factor).