Figure 7
From: A deficiency of uPAR alters endothelial angiogenic function and cell morphology
Quantification of in vitro tube formation assay: (A) Quantification of the number of cells adherent on the beads. Increased number of uPAR-/- ECs adhered to the beads compared to WT cells, both in the absence or presence of VEGF. (B) Increased number of sprouts/bead was observed in uPAR-/- cells in the absence or presence of VEGF compared to WT cells. (C) uPAR-/- cells demonstrated increased sprout length compared to WT ECs in the absence and presence of VEGF. Ten beads/treatment/experiment/genotype were analyzed and the graph represents the mean ± SEM of three independent assays. (*) Denotes significance between control WT and uPAR-/- ECs and (**) identifies significance between WT and uPAR-/- ECs in the presence of VEGF. p value were < 0.05 between WT and uPAR-/- cells.