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Table 1 Melanoma tumors have more gross necrosis in CIB1-KO mice.
Tumor growth and angiogenesis is impaired in CIB1 knockout mice
Total Number of Mice
Mice with Tumor Necrosis
Mice with No Tumor Necrosis
% of Mice with Tumor Necrosis
B16 Melanoma Tumors
Lewis Lung Carcinoma Tumors
Tumor necrosis was grossly evident in B16 melanoma tumors that developed in both WT and CIB1-KO mice.
The number of tumors with clear evidence of gross necrosis in CIB1-KO mice was statistically significant (p = 0.05), chi-square test with one degree of freedom.
There was no evidence of gross necrosis in Lewis lung carcinoma tumors that developed in both WT and CIB1-KO mice.
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