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Table 1 Melanoma tumors have more gross necrosis in CIB1-KO mice.

From: Tumor growth and angiogenesis is impaired in CIB1 knockout mice

Mouse Genotype Total Number of Mice Mice with Tumor Necrosis Mice with No Tumor Necrosis % of Mice with Tumor Necrosis
B16 Melanoma Tumorsa     
   WT 9 3 6 33.3%
   CIB1-KO 11 7 4 63.6%b
Lewis Lung Carcinoma Tumors     
   WT 8 0 8 0.0%
   CIB1-KO 9 0 9 0.0%c
  1. aTumor necrosis was grossly evident in B16 melanoma tumors that developed in both WT and CIB1-KO mice.
  2. bThe number of tumors with clear evidence of gross necrosis in CIB1-KO mice was statistically significant (p = 0.05), chi-square test with one degree of freedom.
  3. cThere was no evidence of gross necrosis in Lewis lung carcinoma tumors that developed in both WT and CIB1-KO mice.