Histological examination of bone marrow. Bone marrows of T241-VEGF (A) and T241-vector (B) tumor-bearing mice were stained with H&E. Bone marrows of buffer- (C), anti-VEGFR1- (D), or anti-VEGFR2-(E) treated T241-VEGF-bearing mice were stained with H&E. Arrows in panels A and C-E point to the residual hematopoietic islets. Bone matrix were encircled with dashed lines. Bar in panel A and B = 100 μm. Bar in panels C-E = 50 μm.