Table 6 Table showing the chemotherapy induced changes in serum VEGF and platelet release of VEGF in advanced and early breast cancer

sVEGF

μg/ml

Geometric Mean (CI) [n]

ABC

344 (271-437) [35]

287 (219-376) [33]

240 (182-317) [33]

253 (196-327) [33]

344 (248-477) [26]

i) 0.01*

ii) 0.2*

EBC

181 (156-210) [86]

177 (151-207) [81]

134 (114-157) [81]

127 (107-151) [83]

211 (181-246) [83]

i) 0.01**

ii) 0.2**

VEGF released

per platelet

μg/ml/platelet

Geometric mean (CI) [n]

ABC

1.02 (0.8-1.30) [35]

0.92 (0.68-1.23) [28]

0.85 (0.61-1.17) [30]

0.92 (0.72-1.19) [31]

1.03 (0.77-1.39) [25]

i) 0.007*

II) 0.03*

EBC

0.53 (0.45-0.62) [82]

0.51 (0.42-0.63) [67]

0.43 (0.35-0.52) [73]

0.43 (0.34-0.

53) [78]

0.65 (0.54-0.77) [78]

i) 0.007**

ii) 0.03**