Skip to main content

Table 1 Pharmacokinetic parameters of VEGF 121 and VEGF PADS

From: Growth factor purification and delivery systems (PADS) for therapeutic angiogenesis

   

Free VEGF

VEGF PADS

Central compartment volume of distribution

V c

(L)

0.013 ± 0.005

0.013 ± 0.003

Plasma clearance

Cl

(L min-1)

0.0008 ± 0.0003

0.0004 ± 0.0004

Area under curve

AUC

(nmol min L-1)

3,863.8 ± 1,444.6

5,059.0 ± 528.5

Distribution half life

t 1/2 dist

(min)

8.6

7.2

Terminal half life

t 1/2 term

(min)

30.2

52.4