Table 2 Different strategies to inhibit miR function in vivo
From: A brief primer on microRNAs and their roles in angiogenesis
Reagent | Description |
|---|---|
AntagomiRs | Cholesterol conjugated 2’-O-Methyl antisense oligonucleotides |
LNA-AntimiRs | Locked nucleic acid based antisense oligos |
miR sponges | Oligos with multiple miR binding sites to act as competitive inhibitors |
miR-masks | Oligos with gene specific sequences complementary to miR binding sites |