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Figure 2 | Vascular Cell

Figure 2

From: The role of AMP-activated protein kinase in the functional effects of vascular endothelial growth factor-A and -B in human aortic endothelial cells

Figure 2

VEGF-B-stimulated AMPK Thr172 phosphorylation is inhibited by STO-609. A) HAECs were preincubated in the presence or absence of 10 μM STO-609 for 15 min prior to incubation with the indicated concentrations of AICAR for 45 min or VEGF-A and VEGF-B for 5 min and lysates prepared. B) HAECs were incubated with VEGF-A (10 ng/ml) and/or VEGF-B (100 ng/ml) for 5 min and lysates prepared. Lysates were subsequently subjected to immunoblotting with the antibodies indicated. Representative immunoblots are shown, repeated with similar results on three independent sets of lysates.

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Vascular Cell

ISSN: 2045-824X

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