Figure 3

uPAR^-/- ECs exhibited altered proliferation on Vn: (A) WT and uPAR^-/- ECs were seeded on Vn-coated plates at a density of 1 × 10⁵ cells/ml as described. Graph represents total cell counts measured at 24 and 48 hr (mean ± SEM) of three independent assays. At both time points proliferation of uPAR^-/- ECs was significantly diminished compared to WT cells. p values between WT and uPAR^-/- ECs at both time points were <0.05. (B) Proliferation of WT and uPAR^-/- ECs is similar on collagen-coated plates at 24 and 48 hr.